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. 2022 Jul 15;12(7):e961. doi: 10.1002/ctm2.961

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© 2022 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Eigengene proximal versus distal gene expression analysis. Eigengene modules showed enrichment for zinc finger and KRAB domain proteins in module 1; LDL receptors in module 2; DNA repair‐related processes, and hypermutation of immunoglobin genes in module 3; MYB‐related genes in module 4; cell cycle regulation, extracellular matrix and cell adhesion processes in module 6 and 7 and specific signalling pathways including GNRH signalling, oxytocin signalling, antigen processing, and presentation in module 5