TABLE 2.
Results from mixed‐effects models
| Outcome measure | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|
| Condition | Sex | Condition * sex | Condition | Sex | Condition * sex | |
| Cognitive DSST | ||||||
| DSST | ||||||
| No. attempted | 0.105 | 0.914 | 0.236 | 0.073 | 0.763 | 0.156 |
| % Correct | 0.016 | 0.663 | 0.913 | 0.022 | 0.686 | 0.918 |
| DAT | ||||||
| Tracking error | <0.001 | 0.009 | 0.897 | <0.001 | 0.018 | 0.659 |
| Response time | 0.011 | 0.056 | 0.307 | 0.016 | 0.074 | 0.234 |
| PSAT | ||||||
| Response time | <0.001 | 0.526 | 0.860 | <0.001 | 0.297 | 0.635 |
| Number correct | <0.001 | 0.230 | 0.957 | <0.001 | 0.230 | 0.957 |
| Subjective | ||||||
| Strength | <0.001 | 0.551 | 0.761 | <0.001 | 0.356 | 0.792 |
| Liking | <0.001 | 0.428 | 0.486 | <0.001 | 0.181 | 0.390 |
| Stoned | <0.001 | 0.970 | 0.739 | <0.001 | 0.755 | 0.458 |
| Sedated | <0.001 | 0.488 | 0.588 | <0.001 | 0.781 | 0.345 |
| Anxious | <0.001 | 0.384 | 0.744 | <0.001 | 0.733 | 0.479 |
| Confident to Drive | <0.001 | 0.188 | 0.824 | <0.001 | 0.298 | 0.784 |
| Physiological | ||||||
| Systolic BP | <.001 | 0.614 | 0.696 | <0.001 | 0.679 | 0.780 |
| Diastolic BP | .016 | 0.803 | 0.106 | 0.040 | 0.736 | 0.134 |
| HR | <0.001 | 0.427 | 0.254 | <0.001 | 0.422 | 0.229 |
| Cannabinoid concentrations | ||||||
| THC | <0.001 | 0.681 | 0.843 | — | — | — |
| 11‐OH‐THC | <0.001 | 0.906 | 0.814 | — | — | — |
| 11‐COOH‐THC | <0.001 | 0.007 | 0.226 | — | — | — |
| CBD | <0.001 | 0.283 | 0.889 | — | — | — |
| 7‐OH‐CBD a | <0.001 | 0.789 | 0.861 | — | — | — |
| 7‐COOH‐CBD a | <0.001 | 0.660 | 0.041 | — | — | — |
a
Data available from study 2 only, BP blood pressure, HR heart rate. Model 1 includes BMI as a covariate; model 2 includes BMI and peak change from baseline THC concentration as covariates.