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. 2022 Jul 15;22(10):1435–1443. doi: 10.1016/S1473-3099(22)00345-0

Table 2.

Vaccine effectiveness by dose and vaccine type in all ages and within age categories against COVID-19

One dose
Two doses
Three doses
BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac
Mild or moderate disease
20–59 years 39·9% (24·8–52·3) 32·7% (14·4–47·6) 35·1% (26·6–42·5) 25·1% (14·7–34·3) 73·5% (66·6–79·2) 51·0% (39·6–60·4)
≥60 years None* None* None* None* 70·2% (53·3–82·0) 32·4% (8·3–51·0)
Severe or fatal disease
20–59 years 95·4% (90·7–98·1) 74·8% (63·7–82·8) 96·3% (94·9–97·3) 91·7% (88·7–94·0) 98·6% (97·5–99·3) 98·8% (97·5–99·5)
60–69 years 70·0% (51·8–82·0) 54·2% (36·4–67·3) 91·1% (86·9–94·0) 79·3% (71·8–85·0) 98·9% (97·3–99·6) 97·4% (95·2–98·7)
70–79 years 72·2% (56·7–82·6) 29·2% (7·4–46·1) 89·8% (85·1–93·1) 74·3% (66·5–80·3) 99·0% (97·4–99·7) 95·4% (92·2–97·4)
≥80 years 75·0% (61·1–84·2) 39·0% (20·9–53·0) 86·9% (80·5–91·3) 58·2% (45·1–68·2) 97·1% (93·8–98·7) 97·3% (94·9–98·7)
Death
20–59 years 96·7% (90·9–99·2) 78·2% (64·9–86·9) 96·8% (95·1–98·0) 93·3% (89·9–95·6) 99·2% (97·9–99·7) 99·4% (98·1–99·9)
60–69 years 77·6% (59·9–88·4) 65·6% (49·8–76·8) 92·7% (88·6–95·4) 84·3% (77·8–89·0) 99·0% (97·2–99·8) 99·0% (97·3–99·8)
70–79 years 80·5% (66·3–89·2) 45·3% (25·1–60·3) 92·3% (88·0–95·2) 76·7% (68·5–82·8) 99·4% (97·9–99·9) 97·0% (94·2–98·6)
≥80 years 78·7% (65·5–87·0) 44·8% (26·9–58·4) 90·3% (84·9–93·9) 63·0% (50·3–72·5) 97·5% (94·2–99·0) 97·9% (95·7–99·1)

Data are effectiveness (95% CI).

*

No evidence of protection based on a negative or very small positive point estimate and wide CIs.