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. 2022 Jul 8;2022:6509028. doi: 10.1155/2022/6509028

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Copyright © 2022 Yan Gao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Knocking down Sort1 significantly inhibited proliferation and colony formation in HCC cells. (a) Sort1 expression levels in HCC cell lines and human normal hepatocytes (THLE-2) determined by real-time PCR. (b) Effects of shRNA-Sort1 transfection on Sort1 expression in HepG2 cells determined by fluorescent quantitative PCR. (c) Effect of Sort1 knockdown on HepG2 proliferation determined by CCK-8 assay. (d) Effects of Sort1 knockdown on the clonogenic ability of HepG2 cells based on the colony formation assay. ^∗p < 0.05 and ^∗∗p < 0.01.