Table 1.
Select baseline participant characteristics by HCC development
| Total n = 227 | Did not Develop HCC (n = 213) | Developed HCC (n = 14) | p-value |
|---|---|---|---|
| Mean (SD) or n (%) | Mean (SD) or n (%) | ||
| Age (yr) (mean) | 59.4 (12.4) | 61.4 (10.0) | 0.60 |
| Site | |||
| CS | 96 (45.1) | 9 (64.3) | 0.37 |
| UC | 55 (25.8) | 2 (14.3) | |
| VA | 62 (29.1) | 3 (21.4) | |
| Sex | |||
| Male | 141 (66.2) | 13 (92.9) | 0.04 |
| Female | 72 (33.8) | 1 (7.1) | |
| Race | |||
| White | 177 (83.1) | 11 (78.6) | 0.60 |
| African American | 18 (8.5) | 2 (14.3) | |
| Asian | 11 (5.2) | 1 (7.1) | |
| Other | 7 (3.3) | 0 (0.0) | |
| Ethnicity | |||
| Non-Hispanic/Latinx | 134 (62.9) | 9 (64.3) | 1.00 |
| Hispanic or Latinx | 79 (37.1) | 5 (35.7) | |
| Etiology of Cirrhosis | |||
| HCV | 66 (31.0) | 7 (50.0) | 0.49 |
| Alcohol | 56 (26.3) | 2 (14.3) | |
| HBV | 6 (2.8) | 1 (7.1) | |
| NAFLD | 46 (21.6) | 2 (14.3) | |
| Other | 39 (18.3) | 2 (14.3) | |
| Complication of cirrhosis | |||
| HE | |||
| No | 160 (75.1) | 7 (50.0) | 0.04 |
| Yes | 53 (24.9) | 7 (50.0) | |
| Varices | |||
| No | 86 (40.4) | 4 (28.6) | 0.26 |
| Yes | 127 (59.6) | 10 (71.4) | |
| Ascites | |||
| No | 119 (55.9) | 8 (57.1) | 1.00 |
| Yes | 94 (44.1) | 6 (42.9) | |
| At Least 1 Complication | |||
| No | 61 (28.6) | 3 (21.4) | 0.76 |
| Yes | 152 (71.4) | 11 (78.6) | |
| Diabetes | |||
| No | 161 (75.6) | 11 (78.6) | 1.00 |
| Yes | 52 (24.4) | 3 (21.4) | |
| AFP (ng/mL) (mean) | 5.13 (21.96) | 4.25 (3.56) | 0.88 |
| MELD (mean) | 9.7 (6.1) | 10.9 (7.8) | 0.46 |