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. 2022 Jul 15;12:12086. doi: 10.1038/s41598-022-14963-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene enrichment analysis: functional terms and KEGG pathways. (A) g:Profiler Manhattan plot. The x axis shows the functional terms (term size greater than 50), grouped and colour-coded by data source (red = GO molecular function, orange = GO biological process, green = GO cellular component, pink = KEGG database). The position of terms in the plots is fixed and terms from the same gene ontology branch are close to each other. The size of circles shows the corresponding term size. Numbers correspond to the terms in the table below; the full list of terms is available in Supplementary Table 3. (B) Legend gene enrichment analysis. The table shows the ID referred to the Manhattan plot above, source database, term ID, term name, adjusted p values after FDR correction. See Supplementary Table 3 for the full list of terms.