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. 2022 Jul 15;12:12068. doi: 10.1038/s41598-022-15946-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Regression of primary tumor and metastases in Patient 6. A primary tumor is visible in the liver prior to the study start (blue box, day -39) but only the tumor-free cavity remains in subsequent images throughout the course of the study. In the lung, multiple metastases present as white spots throughout the first 82 days of imaging but are undetectable by day 160 and remain so for the remainder of the study. All images are MRI with the exception of day −39 for the liver, which is CT.