. 2022 Jul 15;12:12074. doi: 10.1038/s41598-022-16022-8

Table 5.

Biochemical parameters for various experimental groups (1 month).

Groups	C	nCB	CB10	CB40	ANOVA
Groups	C	nCB	CB10	CB40	F-ratio	P-value
AST (U/ml)	37.2 ± 3.32^b	47.5 ± 2.78^a	39 ± 1.75	42.5 ± 4.25	2.075	NS
ALT (U/ml)	13.0 ± 0.7^bcd	9.0 ± 1.03^a	8.3 ± 1.20^a	8.1 ± 1.15^a	4.830	0.011
ALP (IU/l)	120 ± 3.03^bcd	154 ± 9.83^a	149 ± 6.15^a	146 ± 8.9^a	4.134	0.020
LDH (U/l)	691 ± 10.1^cd	658 ± 20.9^d	615 ± 24.5^a	590 ± 29.2^ab	4.062	0.021
Albumin (g/dl)	3.26 ± 0.09	2.90 ± 0.14^d	2.98 ± 0.18^d	3.67 ± 0.14^bc	5.992	0.004
Total protein (g/dl)	6.73 ± 0.28^bc	5.93 ± 0.12^a	5.22 ± 0.32^ad	6.04 ± 0.25^c	5.980	0.004
CK-MB (U/l)	88.8 ± 6.2^cd	84.0 ± 5.7^d	70.7 ± 6.4^a	64.2 ± 5.2^ab	3.734	≤ 0.05
Urea (mg/dl)	33.7 ± 2.3^b	43.9 ± 1.8^acd	33.4 ± 1.4^b	30.1 ± 2.2^b	9.517	≤ 0.001
UA (mg/dl)	2.35 ± 0.10	2.81 ± 0.19	2.41 ± 0.33	2.36 ± 0.24	0.920	NS
Creatinine (mg/dl)	0.526 ± 0.0^bc	0.689 ± 0.03^ad	0.673 ± 0.03^ad	0.521 ± 0.03^bc	12.254	≤ 0.001
BUN	15.7 ± 1.07^b	20.5 ± 0.82^acd	15.6 ± 0.66^b	14.1 ± 1.01^b	9.517	≤ 0.001
Glucose (mg/dl)	51.7 ± 2.6^bcd	78.7 ± 3.9^ad	70.2 ± 2.8^a	63.0 ± 2.6^ab	14.543	≤ 0.001
TSH (µg/dl)	1.024 ± 0.04^cd	0.993 ± 0.06^cd	0.734 ± 0.04^abd	0.578 ± 0.02^abc	24.168	≤ 0.001
FT3 (pmol/l)	8.83 ± 0.60^bcd	7.92 ± 0.44^acd	7.35 ± 0.53^ab	6.18 ± 0.40^ab	4.993	= 0.01
Testosterone (ng/ml)	2.03 ± 0.2^cd	1.99 ± 0.1^cd	1.52 ± 0.09^ab	1.48 ± 0.09^ab	4.065	≤ 0.05

Values are expressed as mean ± S.E, value (a) is significantly different as compared with the control group, value (b) is significantly different as compared with nCB, value (c) is significantly different as compared with CB10, and value (d) is significantly different as compared with CB40.

ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, LDH lactate dehydrogenase, CK-MB creatine kinase–MB, TSH thyroid-stimulating hormone, F T3 free triiodothyronine, UA uric acid, BUN blood urea nitrogen.