Table1.

Mobility prediction and antibiotic resistance genes of the plasmid clusters A-T from the network.

ID	Mobility	Groups	ARGs	Locality/Continent	Samples/Hosts
A	Non-mobilizable	H/M/T	dfrf (Hadza)	Asia,Europe,N./S. America	Avian, Food, Human, Housefly, Cattle, Rat
B	Mobilizable	H/M	–	Eastern Asia, Europe, New Zealand, USA	Avian, Environment, Food, Human, Cattle
C	Non-mobilizable	H/M	–	China, Europe, Islas Malvinas, USA	Avian, Human, Housefly, Livestock, Rat
D	Non-mobilizable	H/M	–	Denmark, Islas Malvinas	Rat
E	Non-mobilizable	H/Y	–	Africa, Asia, Australia, Europe, USA	Environment, Food, Human, Cattle, Rat, Sewage
F	Non-mobilizable	H/Y	tem, aph (H) tem (Y)	China,France	Environment, Food
G	Mobilizable	H/Y	–	Africa, Asia, Australia, Europe, N. America	Avian, Environment, Human, Cattle
H	Mobilizable	H/Y	–	Africa, Australia, China, Europe, USA	Environment, Human, Swine
I	Mobilizable	H/Y	–	Europe, India, N./S. America	Food, Human
J	Mobilizable	H/Y	–	Australia, Asia, Europe, N/S.America	Avian, Canine, Environment, Human, Cattle, Sewage
K	Mobilizable	T/Y	–	Asia, Australia, Europe, USA	Avian, Environment, Human, Livestock, Mollusk
L	Mobilizable	T/Y	–	Africa, Asia, Australia, Europe, N. America	Avian, Canine, Environment, Food, Human, Livestock
M	Conjugative	M	fosA	Africa, Asia, Australia, Europe, USA	Avian, Canine, Human, Livestock, Panda
N	Mobilizable	M	ctx	Asia, Australia, Europe, N./S. America	Human
O	Conjugative	H	aph, tet	Asia, Europe, N. America	Avian, Canine, Human, Livestock
P	Conjugative	T	ctx	Asia, Europe, USA	Avian, Human
Q	Mobilizable	T	tetB	Asia, Australia, Europe, N. America	Human, Livestock
R	Non-mobilizable	Y	tetU	–	–
S	Mobilizable	Y	tem	Asia, Europe, Oceania, N./S. America	Avian, Canine, Human, Livestock
T	Mobilizable	Y	qnrB	Asia, Europe, N./S. America	Avian, Human

The hosts and niches shown refer to the plasmids that had high similarity to this cluster by blast analysis. Groups: H—Hadza; M—Matses, T—Tunapuco, Y—Yanomami.