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. 2022 Jul 15;12:12151. doi: 10.1038/s41598-022-16321-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Phytochemical contents of C. gigiantea stem bark extracts, (a) total cardiac glycoside content (mg DXE/g extract), (b) total triterpenoid content (mg UAE/g extract), (c) total phenolic content (mg GAE/g extract), (d) total flavonoid content (mg RTE/g extract), (e) total alkaloid content (mg BCE/g extract) and (d) Calactin content (mg calactin/10 g extract), where DXE is digoxin equivalent, UAE is ursolic acid equivalent, GAE is gallic acid equivalent, RTE is rutin equivalent and BCE is berberine chloride equivalent. CGEtOH, CGDCM, CGEtOAc, and CGW are the total ethanolic extract, dichloromethane fraction, ethyl acetate fraction and water fraction of C. gigantea stem bark, respectively.