Table 2.
Univariate logistic regression analysis for factors associated with involvement of three or more axillary lymph nodes.
| Characteristics | 3 or more LN( +) (%) | 2 or less LN( +) (%) | p-value |
|---|---|---|---|
| Age (years), mean | 51.5 | 50.6 | 0.048 |
| Mean tumor size by US (cm) | 2.83 ± 1.07 | 2.05 ± 1.01 | < 0.001 |
| Mean tumor size by MRI (cm) | 3.25 ± 1.47 | 2.38 ± 1.41 | < 0.001 |
| Tumor stage by US (cm) | < 0.001 | ||
| T1 (≤ 2) | 541 (57.5) | 25 (28.1) | |
| T2 (> 2–5) | 400 (42.5) | 64 (71.9) | |
| Axillary US classification | < 0.001 | ||
| Gr 1 | 5 (5.7) | 338 (36.6) | |
| Gr 2 | 16 (18.4) | 362 (39.2) | |
| Gr 3 | 17 (19.5) | 151 (16.3) | |
| Gr 4 | 24 (27.6) | 39 (4.2) | |
| Gr 5 | 25 (28.7) | 34 (3.7) | |
| PET/CT-ALN (SUV) | < 0.001 | ||
| Positive (≥ 1.4) | 52 (61.9) | 136 (17.7) | |
| Negative (< 1.4) | 32 (38.1) | 633 (82.3) | |
| Estrogen receptor | 0.716 | ||
| Positive | 68 (76.4) | 723 (78.1) | |
| Negative | 21 (23.6) | 203 (21.9) | |
| Progesterone receptor | 0.853 | ||
| Positive | 55 (64.0) | 606 (65.0) | |
| Negative | 31 (36.0) | 327 (35.0) | |
| HER2 receptor | 0.659 | ||
| Positive | 23 (34.3) | 241 (31.7) | |
| Negative | 44 (65.7) | 519 (68.3) |
Values are presented as mean ± standard deviation or number (%). Abbreviations: ALN, Axillary lymph node; LN, Lymph node; US, Ultrasonography; Gr, Grade; MRI, Magnetic resonance imaging; PET/CT, Positron emission tomography/computed tomography; HER2, Human epidermal growth factor receptor 2.