Table 2.
Variables With Significance in the Univariate Logistic Regression Analysis for a Low Humoral Response (<100 AU/mL) in LTRs After a Third SARS-CoV-2 Vaccination Based on the Anti-S RBD Immunoassay
| Univariate OR (95% CI) | P | Multivariate OR (95% CI) | P | |
|---|---|---|---|---|
| Vaccination <1 y post LT (n = 10/106) | 3.80 (1.01–14.42) | .049 | 8.00 (1.34–47.77) | .023 |
| Arterial hypertension (n = 80/106) | 4.84 (1.06–22.17) | .042 | 5.93 (0.90–39.22) | .065 |
| eGFR, <45 mL/min (n = 33/106) | 6.69 (2.52–17.77) | < .001 | 4.72 (1.56–14.38) | .006 |
| Lymphocytes, <1.3/nla (n = 52/106) | 6.13 (2.09–17.97) | .001 | 5.02 (1.53–16.42) | .008 |
Note: Boldface P values indicate statistical significance.
Anti-S RBD, Anti-SARS-CoV-2 receptor-binding domain; CI, confidence interval; eGFR, estimated glomerular filtration rate; IS, immunosuppression; LT, liver transplantation; LTR, liver transplant recipient; OR, odds ratio; SARS-CoV-2, severe acute respiratory syndrome coronavirus type 2.
a
Median of overall LT cohort.