Fig. 8.

Antioxidant enzymes in human skeletal muscle in response to incremental exercise to exhaustion in normoxia and severe hypoxia, and post-exercise ischaemia. Levels of protein expression of (A) GR, (B) Trx1, (C) Gpx1 and (D) TrxR1. Nx: normoxia session (F_IO₂ = 0.21, P_IO₂ = 143 mmHg); Hyp: severe normobaric hypoxia session (F_IO₂ = 0.104, P_IO₂ = 73 mmHg); Pre: before exercise; Post: 10 s after exercise cessation during ischaemic recovery; Oc1m: 60 s after exercise cessation during ischaemic recovery; FC1m: 60 s after exercise cessation during recovery with free circulation. For panel (A), n = 11 for all conditions except for Oc1m Nx (n = 9) and Post Hyp (n = 10) and for panels (B), (C) and (D), n = 11 except for Oc1m Nx (n = 9). See Fig. 1 for a detailed description of the experimental phases. The statistical analysis was performed with logarithmically transformed data for GR. Values presented are means ± standard errors and expressed in arbitrary units (a.u.). †p < 0.05 vs. Pre Nx; *p < 0.05 vs. Pre Hyp; #p < 0.05 vs. Post Hyp.