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. 2022 Jul 16;19:189. doi: 10.1186/s12974-022-02531-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Nafamostat inhibited macrophage and neutrophil infiltration after SCI. A Immunofluorescence image of CD31 (red) and CD68 (green) in posterior horn of spinal cord at 3 dpi. Cell nuclei were stained with DAPI (blue). Scale bar = 50 μm. B Immunofluorescence image of CD31 (red) and MPO (green) in posterior horn of spinal cord at 3 dpi. Cell nuclei were stained with DAPI (blue). Scale bar = 50 μm. C Illustration describing the image acquisition area in this figure. Fluorescent photos were acquired at the posterior horn of the spinal cord. D Quantitative analysis of the amount of CD68⁺ cells in posterior horn of spinal cord at 3 dpi. All data represent mean ± SEM. *P < 0.05 and **P < 0.01 vs. injury (one-way ANOVA with Tukey's post hoc test, n = 3). E Quantitative analysis of the amount of MPO.⁺ cells in posterior horn of spinal cord at 3 dpi. All data represent mean ± SEM. ***P < 0.001, ****P < 0.0001 vs injury (one-way ANOVA with Tukey's post hoc test, n = 3)