Fig. 1.
PRDX3 expression is decreased in fibrotic liver tissues from humans and mice. (A) The PRDX3, Col1a1, and α-SMA protein levels in liver tissues from patients with mild fibrosis (n = 6) or severe fibrosis (n = 8) were analyzed. (B–D) Mice were injected with CCl4 or subjected to BDL. (B) Liver PRDX3, Col1a1, α-SMA proteins, n = 6. (C) Col1a1 and α-SMA mRNA levels, n = 6. (D) H&E, Masson, Sirius Red staining, n = 6, and IHC staining for PRDX3 and α-SMA, n = 3. Scale bar: 200 μm ##P < 0.01. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)