Table 3.
Clinicopathologic characteristics of patients by PD-1 expression
| Clinicopathologic parameters | PD-1 | ||
|---|---|---|---|
| Positive | Negative | P-value | |
| age | 0.01 | ||
| ≤ 50 | 7 (17.5%) | 33(82.5%) | |
| >50 | 12(12.0%) | 88(88.0%) | |
| tumor size | 0.416 | ||
| ≤ 2.0 cm | 11 (13.3%) | 72 (86.7%) | |
| > 2.0 cm | 8(14.0%) | 49(86.0%) | |
| Menopausal status | 0.171 | ||
| postmenopausal | 10(10.8%) | 83(89.2%) | |
| menstruating | 9(19.1%) | 38(80.9%) | |
| Histological subtype | 0.902 | ||
| IDC | 15(13.4%) | 97(86.6%) | |
| ILC | 4(14.3%) | 24(85.7%) | |
| Histological classification of IDC | 0.243 | ||
| I | 2(6.9%) | 27 (93.1%) | |
| II | 7 (20.0%) | 28 (80%) | |
| III | 6 (12.5%) | 42 (87.5%) | |
| Nodal metastasis | < 0.01 | ||
| Present | 16 (25.8%) | 46 (74.2%) | |
| Absent | 3 (3.8%) | 75 (96.2%) | |
| Lymphovascular Invasion | < 0.01 | ||
| Present | 16 (37.2%) | 27 (62.8%) | |
| Absent | 3 (3.1%) | 94 (96.9%) | |
| Ki-67 Index | 0.019 | ||
| <14% | 9 (27.2%) | 24(72.8%) | |
| >14% | 10(9.3%) | 97(90.7%) | |
| TNM Clinical Stage | < 0.01 | ||
| I ~ II | 6 (6.1%) | 92 (93.9%) | |
| III ~ IV | 13 (31.0%) | 29 (69.0%) | |
| ER | 0.047 | ||
| Positive | 7(8.5%) | 75(91.5%) | |
| Negative | 12(25.0%) | 46(75.0%) | |
| PR | 0.161 | ||
| Positive | 2(6.1%) | 31(93.9%) | |
| Negative | 17(15.9%) | 90(84.1%) | |
| HER-2 | 0.596 | ||
| Positive | 6(16.2%) | 31(83.8%) | |
| Negative | 17(16.5%) | 86(83.5%) | |