Figure 2. Forest plot: association of factor VIII types (recombinant and plasma-derived) with overall inhibitors development – OR (A); HR (B).

The odds ratio (OR) overall inhibitor development analysis (A) used nine studies [17-25], while the hazard ratio overall inhibitor development analysis (B) used seven studies [17,19-22,24,25].

rFVIII: recombinant factor VIII; pdFVIII: plasma-derived factor VIII