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Best-corrected visual acuity variation (in ETDRS letters) by groups until 48 months (primary outcome).
| ETDRS letter changes | 12 months (n = 35) | 24 months (n = 35) | 36 months (n = 33) | 48 months (n = 28) |
|---|---|---|---|---|
| ≥ + 15 letters | 8 (22.9%) | 7 (20.0%) | 7 (21.2%) | 6 (21.4%) |
| +6 to + 14 letters | 4 (11.4%) | 5 (14.3%) | 5 (15.2%) | 3 (10.7%) |
| +5 to −5 letters | 16 (45.7%) | 15 (42.9%) | 15 (45.5%) | 12 (42.9%) |
| −6 to −14 letters | 3 (8.6%) | 3 (8.6%) | 1 (3.0%) | 3 (10.7%) |
| ≤ − 15 letters | 4 (11.4%) | 5 (14.3%) | 5 (15.2%) | 4 (14.3%) |
