Table 2.
Clinical demographics and clinical characteristics of patients in noncirrhosis and cirrhosis groups.
| Total (N = 694) | Noncirrhosis (N = 661)# | Cirrhosis (N = 33)## | p value | |
|---|---|---|---|---|
| Age, yr | 42 (34, 52) | 42 (33, 52) | 40 (35, 49) | 0.605 |
| Male, N (%) | 360 (52) | 335 (51) | 25 (76) | 0.000 |
| ALT, U/L | 21 (11, 53) | 16 (10, 51) | 107 (53, 448) | 0.000 |
| AST, U/L | 26 (19, 46) | 23 (19, 40) | 99 (47, 376) | 0.000 |
| BUN, mmol/L | 4.7 ± 1.5 | 4.7 ± 1.5 | 4.7 ± 1.3 | 0.858 |
| Cr, μmol/L | 67 (57, 79) | 79 (67, 88) | 67 (60, 80) | 0.374 |
| RBC, 1012/L | 4.7 ± 0.5 | 4.7 ± 0.5 | 4.5 ± 0.5 | 0.021 |
| PLT, 109/L | 199 ± 61 | 203 ± 60 | 141 ± 42 | 0.000 |
| WBC, 109/L | 5.9 ± 3.0 | 5.9 ± 3.1 | 4.9 ± 1.5 | 0.001 |
| Glucose, mmol/L | 4.8 (4.4, 5.2) | 4.7 (4.4, 5.2) | 4.9 (4.4, 5.5) | 0.462 |
| sGDNF, pg/ml | 25.2 (11.4, 29.5) | 23.5 (10.9, 29.5) | 33.8 (29.3, 39.4) | 0.000 |
Noncirrhosis is defined by health controls and F0–F3; cirrhosis is defined by F4. The data are expressed as mean ± standard deviation or median (25%–75%). ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; Cr, creatinine; PLT, platelet count; RBC, red blood cell; sGDNF, serum GDNF; WBC, white blood cell.