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. 2022 Apr 28;40(4):789–797. doi: 10.1007/s10637-022-01248-0

Table 3.

Prognostic factors for death (n = 87)

Variables Univariate HR (95% CI) p value Multi-variates HR (95% CI) p value
General
 Age ≥ 60 1.1 (0.5–2.8) 0.79
 Male 0.7 (0.3–1.7) 0.40
 HBV 0.6 (0.2–1.5) 0.27
 HCV 3.3 (0.9–13.0) 0.08 2.3 (0.5–10.0) 0.26
 CPS class B 2.1 (0.8–5.5) 0.13
 Nivolumab used 0.4 (0.2–1.0) 0.05 0.2 (0.1–0.7) 0.01
HCC status
 PVT 2.9 (1.1–7.3) 0.03 4.3 (1.5–12.8) 0.01
 Metastasis 1.0 (0.4–2.6) 0.94
 AFP > 400 (ng/mL) 2.6 (1.1–6.4) 0.03 3.3 (1.1–9.3) 0.03

CPS Child–Pugh score, PVT portal vein thrombosis, AFP alpha- fetoprotein