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. 2022 Jul 16;12:12177. doi: 10.1038/s41598-022-16127-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The frequency of cells co-expressing key transcription factors at the single-cell level is lower in adult endothelial cells compared to embryonic ones. (a) Dot plots showing the frequency and level of expression of the indicated transcription factor coding genes in embryonic and adult endothelial cells; (b) Heatmap showing the relative co-expression of the indicated transcription factor coding genes in embryonic and adult endothelial cells.