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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Liver Transpl. 2022 Jun 16;28(8):1321–1331. doi: 10.1002/lt.26460

Table 1:

Baseline Characteristics of Patients with and without Cirrhotic Cardiomyopathy (CCM) By the Original and Revised Definition

Original CCM Definition Revised CCM Definition
Demographic Variables No CCM (N = 48) CCM (N = 162) No CCM (N = 146) CCM (N = 64)
Age 56 60 58 60
MELD at Transplant 29 28 28 28
Male Gender 28 (58%) 97 (60%) 94 (64%) 31 (48%)
Race
White 47 (98%) 153 (94%) 141 (97%) 59 (92%)
Black -------- 6 (4%) 2 (1%) 4 (6%)
Other 1 (2%) 3 (2%) 3 (2%) 1 (2%)
Disease Etiology
Non-Alcoholic Fatty Liver Disease 8 (17%) 61 (38%) 45 (31%) 24 (38%)
Alcohol-Associated Liver Disease 12 (25%) 39 (24%) 40 (28%) 11 (17%)
Hepatitis C Viral Infection 13 (27%) 28 (17%) 27 (18%) 14 (22%)
Other Etiologies 15 (31%) 34 (21%) 34 (23%) 15 (23%)
Smoking Pre-Transplant 18 (38%) 64 (40%) 53 (36%) 29 (45%)
BMI > 30 Pre-Transplant 8 (17%) 79 (48%) 55 (38%) 30 (47%)
Hypertension 8 (17%) 27 (17%) 25 (17%) 10 (16%)
Diabetes 3 (6%) 29 (18%) 25 (17%) 7 (11%)
Pre-Transplant Statin Use 6 (12%) 37 (23%) 29 (20%) 14 (22%)
Pre-Transplant Antiplatelet Therapy 19 (40%) 71 (44%) 59 (40%) 31 (48%)
Pre-Transplant Beta Blocker Use 34 (71%) 105 (65%) 97 (66%) 42 (66%)
Pre-Transplant Aldosterone Antagonists 47 (98%) 133 (82%) 123 (83%) 57 (89%)
Echocardiographic Variables (median) No CCM (N = 48) CCM (N = 162) No CCM (N = 146) CCM (N = 64)
Septal e’ (n = 201) 9.8 8 8.5 7.2
Lateral e’ (n = 204) 12 11 12 9.1
Average E/e’ Ratio (n = 201) 8.9 9.1 8.5 11.9
Tricuspid Regurgitant Maximal Velocity (n=183) 2.5 2.5 2.4 2.8
Left Atrium Volume Index (n = 202) 33 28 26 38
Mitral Valve Deceleration Time (n = 209) 170 246 218 252
Ejection Fraction (n = 210) 66 66 65 67
E/A Ratio
E/A ≤ 0.8 ------ 36 (23%) 23 (16%) 13 (22%)
E/A 0.9–1.9 43 (90%) 110 (71%) 112 (77%) 41 (71%)
E/A ≥2 5 (10%) 9 (6%) 10 (7%) 4 (7%)