Table 1.
Baseline characteristics of the Low Dose (0.3 mg) Melatonin and High Dose (5.0 mg) Melatonin groups.
| Low Dose n=12 mean (std dev) | High Dose n=12 mean (std dev) | T value or Z valuea | P-value | |
|---|---|---|---|---|
| Age (years) | 64.67 (6.15) | 63.75 (6.68) | −0.35 | 0.73 |
| Sex | 6M, 6F | 5M, 7F | 0.168 | 0.682 |
| Habitual Bedtime | 23.12 (0.54) | 22.69 (0.86) | −0.146 | 0.158 |
| Habitual Waketime | 7.13 (0.52) | 6.83 (0.78) | −0.347 | 0.729 |
| Morningness Eveningness Score | 59.86 (6.15) | 63.11 (9.83) | 0.678 | 0.498 |
| Baseline Sleep Efficiency (%) | 80.83 (5.38) | 78.59 (8.24) | −0.791 | 0.437 |
| Stage 1 (min) | 53.46 (31.64) | 51.81 (23.77) | −0.144 | 0.887 |
| Stage 2 (min) | 202.94 (27.59) | 176.23 (41.70) | −1.850 | 0.078 |
| SWS (min) | 42.83 (36.39) | 59.79 (33.88) | 1.181 | 0.250 |
| REM (min) | 86.81 (26.02) | 88.10 (19.33) | 0.138 | 0.892 |
| TST (min) | 386.04 (24.98) | 375.94 (39.66) | −0.747 | 0.463 |
| Wake (min) | 91.94 (25.59) | 102.54 (39.68) | 0.778 | 0.445 |
| SoL (min) | 18.39 (17.37) | 19.58 (19.54) | −0.123 | 0.902 |
| Awakenings (n) | 28.42 (9.86) | 28.79 (17.43) | −0.549 | 0.583 |
| Awakenings (average duration) | 3.78 (2.31) | 4.09 (1.91) | 0.779 | 0.436 |
std dev=standard deviation; min=minutes, SWS=slow wave sleep, REM=rapid eye movement sleep; TST= total sleep time, SoL=sleep onset latency.
a
Wilcoxon Rank Sum test