Table 2.
Characteristics of the allele and genotype frequencies of the rs8068318 TBX2 and rs1042838 PGR polymorphic locus in women with preeclampsia and the control group
| Locus | Alleles, genotypes | Preeclampsia (n=219) No (%) | Control group (n=329) No (%) | OR (95%CI) | Р-value |
|---|---|---|---|---|---|
| rs8068318 TBX2 | C/C | 24 (11.48%) | 20 (6.45%) | 2.12 (1.14-3.92) | 0.02 |
| C/T | 73 (34.93% ) | 119 (38.51%) | 0.90 (0.62-1.30) | 0.57 | |
| T/T | 112 (52.59%) | 171 (55.34%) | 0.96 (0.66-1.38) | 0.82 | |
| C | 0.29 | 0.26 | 1.21 (0.91-1.61) | 0.19 | |
| T | 0.71 | 0.74 | 0.85 (0.64-1.14) | 0.29 | |
| rs1042838 PGR | T/T | 6 (2.80%) | 7 (2.15%) | 1.31 (0.39-4.41) | 0.85 |
| G/T | 66 (30.84%) | 80 (24.62%) | 1.39 (0.93-2.07) | 0.11 | |
| G/G | 142 (66.36%) | 238 (73.23%) | 0.73 (0.50-1.08) | 0.12 | |
| T | 0.18 | 0.14 | 1.35 (0.97-1.89) | 0.08 | |
| G | 0.82 | 0.86 | 0.76 (0.54-1.07) | 0.12 |
Note: OR: odds ratio; CI: confidence interval; Р-value: significance level; bold characters indicate a significant difference.