Table 2.
Echocardiographic findings
| Variables | All patients (n = 81) | BNP ≤ 61.4 pg/mL (n = 41, 50.6%) | BNP > 61.4 pg/mL (n = 40, 49.4%) | P‐value |
|---|---|---|---|---|
| LVEF, % | 57.8 ± 5.0 | 58.5 ± 4.7 | 57.0 ± 5.3 | 0.161 |
| Left ventricular global longitudinal strain, % | −17.9 ± 3.2 | −18.7 ± 2.6 | −17.1 ± 3.6 | 0.029 |
| LVEDV index, mL/m2 | 73.6 ± 18.1 | 72.3 ± 18.1 | 75.0 ± 18.4 | 0.513 |
| LVESV index, mL/m2 | 31.4 ± 9.8 | 30.3 ± 9.7 | 32.5 ± 10.1 | 0.315 |
| SV index, mL/m2 | 48.4 ± 7.5 | 48.1 ± 7.4 | 48.7 ± 7.8 | 0.729 |
| Interventricular septal thickness, mm | 10.3 ± 1.4 | 10.0 ± 1.2 | 10.7 ± 1.6 | 0.030 |
| Posterior wall thickness, mm | 10.1 ± 1.3 | 9.7 ± 1.2 | 10.5 ± 1.3 | 0.006 |
| Left ventricular mass index, g/m2 | 110.1 ± 24.7 | 103.5 ± 19.7 | 116.9 ± 27.8 | 0.014 |
| Relative wall thickness | 0.44 ± 0.06 | 0.42 ± 0.05 | 0.45 ± 0.07 | 0.022 |
| Left atrial volume index, mL/m2 | 38.6 ± 22.2 | 31.4 ± 10.3 | 46.0 ± 28.4 | 0.003 |
| Ascending aorta dimension, mm | 34.6 ± 4.1 | 35.2 ± 4.3 | 33.9 ± 4.0 | 0.161 |
| PASP, mmHg | 30.4 ± 7.8 | 28.2 ± 4.7 | 32.6 ± 9.7 | 0.011 |
| AVA index, cm2/m2 | 0.64 ± 0.04 | 0.65 ± 0.05 | 0.64 ± 0.03 | 0.432 |
| Peak AV velocity, m/s | 3.38 ± 0.29 | 3.37 ± 0.30 | 3.38 ± 0.27 | 0.861 |
| Peak AVPG, mmHg | 45.9 ± 7.9 | 45.8 ± 8.4 | 46.0 ± 7.5 | 0.903 |
| Mean AVPG, mmHg | 25.1 ± 5.2 | 25.2 ± 5.5 | 25.0 ± 4.9 | 0.857 |
| Velocity ratio | 0.32 ± 0.06 | 0.31 ± 0.06 | 0.33 ± 0.06 | 0.135 |
| Bicuspid aortic valve, n | 11 (13.6) | 7 (17.1) | 4 (10.0) | 0.519 |
| Vena contracta width, mm | 4.2 ± 0.7 | 4.0 ± 0.6 | 4.3 ± 0.8 | 0.028 |
| AR jet width/LVOT width, % | 35.4 ± 5.6 | 35.5 ± 5.8 | 35.3 ± 5.6 | 0.902 |
| Moderate MR, n | 4 (4.9) | 0 (0.0) | 4 (10.0) | 0.055 |
| Moderate MS, n | 0 (0) | 0 (0.0) | 0 (0.0) | Not applicable |
| Moderate/severe TR, n | 6 (7.4) | 0 (0.0) | 6 (15.0) | 0.012 |
AR, aortic regurgitation; AV, aortic valve; AVA, aortic valve area; AVPG, aortic valve pressure gradient; BNP, B‐type natriuretic peptide; LVEDV, left ventricular end‐diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end‐systolic volume; LVOT, left ventricular outflow tract; MR, mitral regurgitation; MS, mitral stenosis; PASP, pulmonary artery systolic pressure; SV, stroke volume; TR, tricuspid regurgitation.
Continuous data are presented as means ± standard deviations; categorical data are given as the counts (percentages).