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. 2022 Apr 18;9(4):2070–2083. doi: 10.1002/ehf2.13939

TABLE 1.

Examples of echocardiographic and cardiac magnetic resonance definitions of left ventricular reverse remodelling in selected studies

Reference Number of patients Time of evaluation (months) LVRR definition
Echocardiography
Merlo et al. 5 361 patients with idiopathic DCM 24

LVEF increase ≥ 10% or LVEF ≥ 50%

iLVEDD decrease ≥ 10% or iLVEDD ≤ 33 mm/m2

Chung et al. 6 498 HFrEF patients (267 with NICM) 6 LVESV reduction ≥ 15%
Wilcox et al. 7 3994 HFrEF patients (1421 with NICM) 24 LVEF increase > 10%
Brenyo et al. 8 612 HFrEF patients (283 with NICM) 12 LVESV reduction ≥ 15%
Cardiac magnetic resonance
Masci et al. 9 58 patients with idiopathic DCM 24

LVEF increase ≥ 10%

LVEDV decrease ≥ 10%

DCM, dilated cardiomyopathy; HFrEF, heart failure with reduced ejection fraction; iLVEDD, indexed left ventricular end‐diastolic diameter; LVEDV, left ventricular end‐diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end‐systolic volume; LVRR, left ventricular reverse remodelling; NICM, non‐ischaemic cardiomyopathy.