Table 4.

Spearman’s rho correlations between select independent variables and dependent variable % reduction in wound area in 35 participants with CVLUs—total group

	% Reduction in wound area
	Correlation coefficient (p value)
	Day 28	Day 56
EPA + DHA
Day 28	0.27 (0.13)	0.20 (0.25)
Day 56	0.34 (0.05)*	0.25 (0.16)
EPA
Day 28	0.18 (0.32)	0.30 (0.09)
Day 56	0.28 (0.10)	0.28 (0.11)
DHA
Day 28	0.35 (0.045)*	0.18 (0.30)
Day 56	0.34 (0.046)*	0.24 (0.16)
Total n-3 PUFAs
Day 28	0.31 (0.07)	0.23 (0.18)
Day 56	0.36 (0.03)*	0.28 (0.11)
CD15+ cells in WF
Day 28	−0.18 (0.33)	−0.53 (0.003)**
Day 56	−0.45 (0.008)**	−0.33 (<0.001)**
CD66b+cells in WF
Day 28	−0.28 (0.14)	−0.45 (0.01)*
Day 56	−0.35 (0.04)*	−0.45 (0.009)**
CD66b+/CD15+ cells in WF
Day 28	−0.15 (0.43)	−0.44 (0.02)*
Day 56	−0.35 (0.05)*	−0.43 (0.01)*
MMP-8
Day 28	−0.21 (0.30)	−0.36 (0.06)
Day 56	−0.29 (0.17)	−0.41 (0.04)*
HNE
Day 28	−0.28 (0.29)	−0.02 (0.96)
Day 56	−0.28 (0.23)	−0.22 (0.34)

DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; HNE, human neutrophil elastase; MMP-8, matrix metalloproteinase-8; PUFA, polyunsaturated fatty acids; WF, wound fluid.

^*p≤0.05,

^**p<0.01.