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. 2022 Jul 14;6(1):e001519. doi: 10.1136/bmjpo-2022-001519

Table 3.

Adverse neonatal outcomes associated with second mode of birth in women who had a CS first birth

Outcome Unadjusted OR (95% CI) Adjusted OR (95% CI) P value adjusted OR
Neonatal infection within 28 days Vaginal spontaneous Reference Reference
N=93 430 Vacuum/Forceps 1.70 (1.36 to 2.12) 2.00 (1.58 to 2.53) <0.001
  Planned CS 0.52 (0.42 to 0.64) 0.68 (0.53 to 0.86) 0.002
  Emergency CS 2.85 (2.46 to 3.30) 2.03 (1.71 to 2.40) <0.001
Asphyxia and/or respiratory distress Vaginal spontaneous Reference Reference
N=89 848 Vacuum/Forceps 2.27 (2.01 to 2.56) 2.74 (2.39 to 3.13) <0.001
  Planned CS 1.86 (1.70 to 2.04) 2.16 (1.93 to 2.41) <0.001
  Emergency CS 4.65 (4.28 to 5.06) 3.24 (2.94 to 3.57) <0.001
Neonatal care/hospital care within 28 days Vaginal spontaneous Reference Reference
N=82 429 Vacuum/Forceps 1.52 (1.41 to 1.63) 1.70 (1.57 to 1.84) <0.001
  Planned CS 1.22 (1.16 to 1.29) 1.02 (0.95 to 1.08) 0.603
  Emergency CS 2.67 (2.54 to 2.80) 1.79 (1.69 to 1.90) <0.001
Neonatal death within 28 days Vaginal spontaneous Reference Reference
N=94 261 Vacuum/Forceps 1.79 (0.96 to 3.34) 3.15 (1.55 to 6.39) 0.001
  Planned CS 0.99 (0.60 to 1.62) 1.73 (0.94 to 3.19) 0.077
  Emergency CS 5.35 (3.63 to 7.89) 2.88 (1.82 to 4.57) <0.001

OR was obtained by logistic models. Both unadjusted and adjusted results are presented. P value of adjusted model is presented

Adjusted OR: adjustments were made for mother’s age, smoking, diabetes, BMI, mental illness and prematurity (up to week 36+6) in all adjusted models.

BMI, body mass index; CS, caesarean section.