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. 2022 Jul 4;13:921223. doi: 10.3389/fimmu.2022.921223

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Copyright © 2022 Qi, Zhang, Ren, Xu, Yang, Chen, Tu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of regulator clusters and related biological characteristics. (A) Heatmap of 32 RNA modification regulators among distinct regulator clusters. (B) The OS curve comparing survival of the TCGA-SARC cohort in Regulator Clusters A (blue), Regulator Clusters B (orange), and Regulator Clusters C (red). (C) The infiltration of immune cells within distinct regulator clusters. The box plot extends from the 25th to 75th percentile, and the central parallel line indicates the median. (D, E) The GSVA illustrating pathway enrichment among distinct regulator clusters. ns, p ≥ 0.05; *, 0.01 ≤ p < 0.05; **, 0.001 ≤ p < 0.01; ***, 0.0001 ≤ p < 0.001.