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. 2022 Jul 4;13:907145. doi: 10.3389/fgene.2022.907145

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Copyright © 2022 Zhang, Cai, Lu, Xu, Qu, Zhao and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Co-expression network construction of GSE1563 analyzed by WGCNA. (A) Hierarchical clustering dendrogram of kidney samples in GSE1563 and the corresponding clinical trait heatmap. (B) Analysis of appropriate soft-thresholding powers. The red line indicates a correlation coefficient of 0.85. The second plot shows average network connectivity under weighting coefficients. The third plot indicates the correlation of log (k) and log [P (k)]. (C) Clustering dendrograms of 9,155 genes in 30 samples, from which 14 co-expression modules were constructed with different colors. (D) Heatmap plot depicts the TOM among all genes in the analysis, which shows the interactions among co-expression modules. The stronger intensity of orange indicates greater overlaps.