TABLE 2.

Standard of scoring of 14 RFRGs.

Weight (Total Points)	GSE1563 Regression Analysis	GSE1563 & GSE139061	AUC Curve		GSE30718	GSE85957
	±2	±2	±2		±1	±0.5
If negative correlation/declining trend and p < 0.05	−2	−2	−2		−1	−0.5
If negative correlation/declining trend and p < 0.1	−1	−1	−1		−0.5	0
If positive correlation/increasing trend and p < 0.05	2	2	2		1	0.5
If positive correlation/increasing trend and p < 0.1	1	1	1		0.5	0
If p > 0.1	0	0	0		0	0
	HPA database
Weight (total points)	±1

If negative correlation/declining trend in GSE1563 Regression analysis/GSE1563 & GSE139061	Stained strongly in tubules	−1
	Stained weakly in tubules	−0.5
If positive correlation/increasing trend in GSE1563 Regression analysis/GSE1563 & GSE139061	Stained in tubules	1
	No staining in tubules	0.5
	Dixon 2021 scRNA- Seq Database
Weight (total points)	±2
If declining trend vs. control	Max expression was high	−2
	Max expression was low	−1
If increasing trend vs. control	Max expression was high	2
	Max expression was low	1