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. 2022 Jul 4;13:932013. doi: 10.3389/fphys.2022.932013

TABLE 2.

In-hospital evolution of the entire cohort and according to the presence of abnormal RBC morphologies.

Entire cohort Abnormal RBC morphologies
No (n = 40) <10% (n = 44) >10% (n = 31) p-value
Evolution
Length of hospitalization (days) 13 [9–21] 10 [8–18] 14 [10–28] 14 [9–22] 0.123
ARDS 5 (4.3) 1 (2.5) 1 (2.3) 3 (9.7) 0.309
Need for RBCs transfusion 12 (10.4) 3 (7.5) 4 (9.1) 5 (16.1) 0.483
Maximal O2 therapy needed
 No O2 therapy needed 13 (11.3) 5 (12.5) 8 (18.2) 0
 Standard O2 therapy a 71 (61.7) 29 (72.5) 22 (50.0) 20 (64.5)
 Ventilation/Intubation b 31 (27.0) 6 (15.0) 14 (31.8) 11 (35.5)
 ICU admission 16 (13.9) 1 (2.5) 9 (20.5) 6 (19.4) 0.021
 In-hospital death 27 (23.5) 5 (12.5) 9 (20.5) 13 (41.9) 0.012

Data are presented as n (%) or median [interquartile range]. Statistical significance was set at p < 0.05. p values < 0.05 are indicated in bold.

ARDS, acute respiratory distress syndrome; RBCs, red blood cells; ICU, intensive care unit.

a

Oxygen delivered through nasal cannula, Venturi mask or reservoir mask.

b

Non-invasive ventilatory support or orotracheal intubation.