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. 2022 Jul 4;9:916486. doi: 10.3389/fsurg.2022.916486

Table 7.

Postoperative complications grouped by PPAP and PF occurrence.

PPAP and PF occurrence
p-value
None (n = 119) Only PPAP (n = 100) Only PF (n = 17) Both (n = 50) P 1 P 2
Clavien-Dindo ≥ IIIb, n (%) 2 (1.7) 3 (3.0) 1 (5.9) 10 (20.0) 0.844 0.001
PPH, n (%) 11 (9.2) 13 (13.0) 5 (29.4) 18 (36.0) 0.452 0.001
 A 7 (63.6) 7 (53.8) 2 (40.0) 4 (22.2)
 B 1 (9.1) 4 (30.8) 1 (20.0) 4 (22.2)
 C 3 (27.3) 2 (15.4) 2 (40.0) 10 (55.6)
DGE, n (%) 47 (39.5) 36 (36.0) 13 (76.5) 35 (70.0) 0.359 <0.001
 A 31 (66.0) 17 (47.2) 3 (23.1) 11 (31.4)
 B 14 (29.8) 17 (47.2) 6 (46.2) 15 (42.9)
 C 2 (4.2) 2 (5.6) 4 (30.7) 9 (25.7)
BL, n (%) 1 (0.8) 0 2 (11.8) 1 (2.0) 1 0.333
Intra-abdominal infection, n (%) 36 (30.3) 33 (33.0) 16 (94.1) 45 (90.0) 0.663 <0.001
AKI, n (%) 1 (0.8) 1 (1.0) 1 (5.9) 1 (2.0) 1 1
Bowel obstruction, n (%) 4 (3.4) 3 (3.0) 0 (0) 1 (2.0) 1 1
Wound infection, n (%) 1 (0.8) 0 (0) 0 (0) 2 (4.0) 1 0.110
Abdominal fluid collection, n (%) 19 (16.0) 38 (38.0) 9 (52.9) 33 (66.0) <0.001 0.001
Puncture and drainage treatment, n (%) 4 (3.4) 7 (7.0) 5 (29.4) 21 (42.0) 0.219 <0.001
Secondary operation, n (%) 3 (2.5) 3 (3.0) 1 (5.9) 9 (18.0) 1 0.004
Mortality, n (%) 0 (0) 1 (1.0) 0 (0) 5 (10.0) 0.457 0.027
ICU stay (day) 1.0 (0–2.0) 1.0 (0–2.0) 2.0 (1.0–5.0) 2.0 (0–3.0) 0.874 0.007
Total hospital stay (day) 22.0(18.0–27.0) 22.5(19.0–28.0) 42.0(23.5–54.0) 29.0(23.8–37.0) 0.401 <0.001
Postoperative hospital stays (day) 15.0(12.0–18.0) 16.0(14.0–18.8) 27.0(16.5–39.0) 20.5(15.8–30.5) 0.054 <0.001
Cost ($) 13,685(11,250–16,491) 14,678(12,145–170,723) 23,299(15,373–31,391) 17,758(15,497–23,908) 0.055 <0.001

p1, only PPAP group compared to the none of PPAP and PF occurred group; p2: both PPAP and PF occurred group compared with the only PPAP group; PPAP, postpancreatectomy acute pancreatitis; PF, clinical relevant pancreatic fistula; PPH, postpancreatectomy hemorrhage; DGE, delayed gastric empty; BL, bile leakage; AKI, acute kidney injury; ICU, intensive care unit.