Table 1.
Relationship between KPNA2 expression and clinical characteristics of TSCC patients.
| All cases | KPNA2 | |||
|---|---|---|---|---|
| Low expression | High expression | P | ||
| Gender | ||||
| Female | 44 | 16(36%) | 28(64%) | 0.2597 |
| Male | 80 | 20(25%) | 60(75%) | |
| Age | ||||
| ≥57.8 | 74 | 22(30%) | 52(70%) | 0.9948 |
| <57.8 | 50 | 14(28%) | 36(72%) | |
| pT status | ||||
| 1 | 21 | 11(52%) | 10(48%) | 0.02892 |
| 2 | 43 | 9(21%) | 34(79%) | |
| 3 | 33 | 6(18%) | 27(82%) | |
| 4 | 19 | 5(26%) | 14(74%) | |
| pN status | ||||
| 0 | 48 | 12(25%) | 36(75%) | 0.3065 |
| 1 | 17 | 7(41%) | 10(59%) | |
| 2 | 45 | 10(22%) | 35(78%) | |
| Stage | ||||
| I | 13 | 7(54%) | 6(46%) | 0.0498 |
| II | 19 | 2(11%) | 17(89%) | |
| III | 29 | 8(28%) | 21(72%) | |
| IV | 51 | 12(24%) | 39(76%) | |
| Tumor grade | ||||
| 1 | 17 | 9(53%) | 8(47%) | 0.04655 |
| 2 | 85 | 23(27%) | 62(73%) | |
| 3 | 22 | 4(18%) | 18(82%) | |
pT, posttreatment tumor category; pN, lymph node status; Stage, AJCC prognostic stage grouping; Tumor grade, Tumor grade is a way of classifying tumors based on certain features of their cells.
Grade 1. The tumor cells look the most like normal tissue and are slow-growing (well-differentiated).
Grade 2. The tumor cells fall somewhere in between grade 1 and grade 3 (moderately-differentiated).
Grade 3. The tumor cells look very abnormal and are fast-growing (poorly-differentiated).
Bolded p-values were two-sided with significance defined as a p-value < 0.05.