Figure 2.

Schematic representation of the immune cells and their products in hypoxia condition. From left, the expression of neutrophiles cells multiplies. The expression of M1 macrophages increases and M2 macrophages decreases. The total number of NK cells goes up which in turn increases the glycolytic metabolism. The number of Th17 cells goes up. B cells also increases along with high regulation of antibodies. Th1 cells and T reg cells production decreases due to low oxygen. The number T cytotoxic cells also decrease because of reduced oxygen. The number of DCs increases which intern increases the production of chemokines associated with DCs.