Table 4.
NLRP3 and cytokines concentrations in the serum of patients for Group 2, the patients who received the combination Propofol+Fentanyl
|
Parameter |
Propofol+Fentanyl Group 2 (n=10) |
||||
|
Before MIS |
After MIS |
p-value |
|||
|
Mean ± SD |
95% CI |
Mean ± SD |
95% CI |
||
|
NLRP3 [ng/mL] |
14.82±1.54 |
13.72–15.91 |
16.11±1.54 |
15.00–17.21 |
0.037* |
|
TNF-α [pg/mL] |
12.83±4.79 |
9.39–16.26 |
16.43±4.66 |
13.09–19.76 |
0.089 |
|
IL-6 [pg/mL] |
12.34±4.51 |
9.11–15.56 |
14.89±4.12 |
11.94–17.84 |
0.143 |
|
IL-10 [pg/mL] |
14.58±3.00 |
12.43–16.73 |
17.37±2.89 |
15.30–19.45 |
0.043* |
CI: Confidence interval; IL: Interleukin; MIS: Minimally invasive surgery; NLRP3: Nucleotide-binding domain (NOD) and leucine-rich repeat protein 3; SD: Standard deviation; TNF-α: Tumor necrosis factor-alpha. *Statistically significant