Table 5.
n | Citations | ||||
---|---|---|---|---|---|
Association | No association | ||||
Bi | Multi | Bi | Multi | ||
Clinical | |||||
Higher parity | 2 | 33 | 34 | ||
Hyperthyroidism a | 2 | 86,99 | |||
Bone density or fracture | 2 | 37,69 | |||
Using estrogen/hormone therapy | 2 | 50,76 | |||
Higher gravidity | 1 | 68 | |||
Older age at second abortion | 1 | 71 | |||
Diet (high animal fat) | 1 | 67 | |||
Diet (low soy) | 1 | 100 | |||
Chinese herbal medicine | 1 | 89 | |||
Chinese medical diagnosis | 1 | 114 | |||
Poorer fitness, flexibility, or balance | 2 | 39 | 58 | ||
Alcohol use | 2 | 47,58 | |||
Anthropometrics | 2 | 58,72 | |||
Older age at menopause | 1 | 34 | |||
Body composition b | 1 | 58 | |||
Metabolism c | 1 | 58 | |||
Overall health rating | 1 | 47 | |||
Caffeine intake | 1 | 58 | |||
Diet (low antioxidants) | 1 | 35 | |||
Coronary artery calcium | 1 | 112 | |||
Carotid intima-media thickness | 1 | 112 | |||
Cardio-ankle vascular index | 1 | 58 | |||
Ankle brachial pulse index | 1 | 58 | |||
Heart rate, blood pressure | 1 | 58 | |||
Sympathetic/parasympathetic tone | 1 | 58 | |||
Biomarkers | |||||
Genotype (CYP1B1 Leu432Val) | 2 | 79,80 | |||
Genotype (CYP17 A1 rs743572) | 1 | 77 | |||
Estradiol levels | 1 | 112 | |||
Hashimoto’s antibody present | 1 | 86 | |||
Symptom/QOL | |||||
Worse anxiety | 2 | 58,67 | |||
Worse stress d | 2 | 47,76 |
Bi: bivariate tests for association such as chi-square tests, Mann–Whitney U tests, t-tests, ANOVA, or univariate logistic regression; multi: multivariate or multivariable tests for association such as multiple logistic or multiple regressions that controlled for confounders; CYP: cytochrome P450; QOL: quality of life.
Superscripted numbers are the article reference citations.
Grave’s disease, low thyroid-stimulating hormone (TSH), and high thyroxine (T4).
Included % body fat, muscle mass, water mass, waist–hip ratio, and visceral fat level.
Resting energy expenditure and body temperature.
Perceived stress or occurrence of upsetting events and being pessimistic.