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. 2022 Jul 14;18:17455057221112267. doi: 10.1177/17455057221112267

Table 5.

Unclear correlates of palpitations in peri- and post-menopausal women based on insufficient evidence as determined by number of articles, type of statistical tests, and article results with citations.

n Citations
Association No association
Bi Multi Bi Multi
Clinical
 Higher parity 2 33 34
 Hyperthyroidism a 2 86,99
 Bone density or fracture 2 37,69
 Using estrogen/hormone therapy 2 50,76
 Higher gravidity 1 68
 Older age at second abortion 1 71
 Diet (high animal fat) 1 67
 Diet (low soy) 1 100
 Chinese herbal medicine 1 89
 Chinese medical diagnosis 1 114
 Poorer fitness, flexibility, or balance 2 39 58
 Alcohol use 2 47,58
 Anthropometrics 2 58,72
 Older age at menopause 1 34
 Body composition b 1 58
 Metabolism c 1 58
 Overall health rating 1 47
 Caffeine intake 1 58
 Diet (low antioxidants) 1 35
 Coronary artery calcium 1 112
 Carotid intima-media thickness 1 112
 Cardio-ankle vascular index 1 58
 Ankle brachial pulse index 1 58
 Heart rate, blood pressure 1 58
 Sympathetic/parasympathetic tone 1 58
Biomarkers
 Genotype (CYP1B1 Leu432Val) 2 79,80
 Genotype (CYP17 A1 rs743572) 1 77
 Estradiol levels 1 112
 Hashimoto’s antibody present 1 86
Symptom/QOL
 Worse anxiety 2 58,67
 Worse stress d 2 47,76

Bi: bivariate tests for association such as chi-square tests, Mann–Whitney U tests, t-tests, ANOVA, or univariate logistic regression; multi: multivariate or multivariable tests for association such as multiple logistic or multiple regressions that controlled for confounders; CYP: cytochrome P450; QOL: quality of life.

Superscripted numbers are the article reference citations.

a

Grave’s disease, low thyroid-stimulating hormone (TSH), and high thyroxine (T4).

b

Included % body fat, muscle mass, water mass, waist–hip ratio, and visceral fat level.

c

Resting energy expenditure and body temperature.

d

Perceived stress or occurrence of upsetting events and being pessimistic.