Skip to main content
. 2021 Jun 21;185(10):2976–2985. doi: 10.1002/ajmg.a.62392

FIGURE 2.

FIGURE 2

Z‐score analysis of patient outcome measures compared at baseline and 12‐weeks posttreatment to age and gender matched normative data. Z‐score comparison of (a) grip strength, (b) dorsiflexion strength, (c) plantarflexion strength, (d) long jump, (e) 6 minute walk (MWT), and (f) handwriting speed. (a–d, f) N = 6 NF1 children, (e) N = 5 NF1 children. Z‐score calculated by sample value – normative (age and gender matched) mean/SD. Data present as group mean + SD. p‐Values were assessed by paired T test. *p < 0.05 and **p < 0.01. Normative data were collected through the 1000 Norms project. n = 8 10‐year male, n = 8 10‐year female, n = 8 11‐year male, n = 8 12‐year male, n = 8 12‐year female, n = 10 9‐year male. Normative data were adapted from Cermak (1989) and Wechsler (1974) for (f). Dotted line at 0 represents where NF1 children would have a comparable Z‐score to age and sex matched normative data. Each symbol denotes participants 1–6