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. 2021 Sep 3;188(1):37–45. doi: 10.1002/ajmg.a.62485

TABLE 3.

Summary of hierarchical multivariate regression analysis on relationship between medical, welfare, and educational challenges and parental psychological distress (N = 125)

Adjusted Model 1 Adjusted Model 2
Yes 95% CI 95% CI
N (%) β Lower Upper p β Lower Upper p
Medical challenges
Total number of medical challenges, mean (SD) 2.8 (2.0) 0.246 0.074 0.419 0.006 0.195 0.013 0.377 0.035
Difficulty of going to multiple medical institutions 32 (25.6) 0.214 0.046 0.382 0.013 0.180 0.012 0.349 0.036
Welfare challenges
Total number of welfare challenges, mean (SD) 5.3 (4.4) 0.298 0.125 0.471 0.001 0.264 0.090 0.438 0.003
Lack of consultants and contacts regarding financial support systems 25 (20.0) 0.251 0.081 0.421 0.004 0.237 0.069 0.404 0.006
Lack of knowledge on the part of supporters (welfare facility personnel and government personnel) regarding 22q11.2 deletion syndrome 60 (48.0) 0.284 0.113 0.455 0.001 0.259 0.089 0.429 0.003
No daycare center suitable for the characteristics and traits of the individual with 22q11.2 deletion syndrome 31 (24.8) 0.294 0.124 0.465 0.001 0.268 0.098 0.438 0.002
Unable to go to the daycare center even if one is available 12 (9.6) 0.203 0.026 0.380 0.025 0.162 −0.017 0.341 0.075
No support available when parents are exhausted and need a respite 25 (20.0) 0.352 0.191 0.514 0.000 0.322 0.159 0.486 0.000
Lack of understanding in the workplace 6 (4.8) 0.264 0.089 0.439 0.003 0.239 0.065 0.413 0.008
Lack of residences such as group homes 14 (11.2) 0.194 0.005 0.384 0.045 0.161 −0.028 0.350 0.094

Note: Bold represents statistically significant. Adjusted Model 1: multivariate regression analysis adjusting parental age, parental sex, family income, marital status, child age, and child sex. Adjusted Model 2: multivariate regression analysis adjusting parental age, parental sex, family income, marital status, child age, child sex, and total number of child's comorbidities.

Abbreviations: β, standardized regression coefficient; CI, confidence interval.