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. 2022 Jul 18;22:131. doi: 10.1186/s12873-022-00681-x

Table 2.

How respondents use and interpret capillary refill time

Overall Adult practice Pediatric practice p-value
n = 418 n = 308 n = 110
Would you say that capillary refill time is a reliable measurement in clinical practice, n (%)
 No 34 (8.1) 31 (10.1) 3 (2.7) < 0.001
 Possibly 139 (33.3) 123 (39.9) 16 (14.5)
 Probably 146 (34.9) 96 (31.2) 50 (45.5)
 Certainly 99 (23.7) 58 (18.8) 41 (37.3)
Would you say that capillary refill time is a reproducible measurement in clinical practice, n (%)
 No 37 (8.9) 32 (10.4) 5 (4.5) 0.001
 Possibly 92 (22.0) 79 (25.6) 13 (11.8)
 Probably 129 (30.9) 93 (30.2) 36 (32.7)
 Certainly 160 (38.3) 104 (33.8) 56 (50.9)
According to you, what is the pathological threshold of capillary refill time, n (%)
 It depends on the clinical context; we cannot define a threshold 39 (9.3) 34 (11.0) 5 (4.5) 0.002
 More than 2 seconds 27 (6.5) 13 (4.2) 14 (12.7)
 More than 3 seconds 308 (73.7) 223 (72.4) 85 (77.3)
 More than 5 seconds 43 (10.3) 37 (12.0) 6 (5.5)
 More than 7 seconds 1 (0.2) 1 (0.3) 0 (0.0)
Do you think that capillary refill time can be used to diagnose acute circulatory failure, n (%)
 No 34 (8.1) 27 (8.8) 7 (6.4) 0.012
 Possibly 114 (27.3) 96 (31.2) 18 (16.4)
 Probably 148 (35.4) 103 (33.4) 45 (40.9)
 Certainly 122 (29.2) 82 (26.6) 40 (36.4)
Do you think that capillary refill time has a prognostic value in patients with acute circulatory failure, n (%)
 No 190 (45.5) 122 (39.6) 68 (61.8) 0.001
 Possibly 122 (29.2) 97 (31.5) 25 (22.7)
 Probably 69 (16.5) 58 (18.8) 11 (10.0)
 Certainly 37 (8.9) 31 (10.1) 6 (5.5)
Do you think that capillary refill time is a reliable surrogate marker of tissue perfusion, n (%)
 No 54 (12.9) 45 (14.6) 9 (8.2) 0.206
 Possibly 135 (32.3) 102 (33.1) 33 (30.0)
 Probably 162 (38.8) 112 (36.4) 50 (45.5)
 Certainly 67 (16.0) 49 (15.9) 18 (16.4)
Do you think that capillary refill time is a surrogate marker of cardiac output, n (%)
 No 195 (46.7) 154 (50.0) 41 (37.3) 0.133
 Possibly 150 (35.9) 105 (34.1) 45 (40.9)
 Probably 50 (12.0) 33 (10.7) 17 (15.5)
 Certainly 23 (5.5) 16 (5.2) 7 (6.4)
Do you think that a perfusion goal-directed therapy based on capillary refill time could reduce mortality in patients with acute circulatory failure, n (%)
 No 81 (19.4) 63 (20.5) 18 (16.4) 0.027
 Possibly 182 (43.5) 143 (46.4) 39 (35.5)
 Probably 116 (27.8) 79 (25.6) 37 (33.6)
 Certainly 39 (9.3) 23 (7.5) 16 (14.5)
Do you think that capillary refill time is useful in clinical practice, n (%)
 No 18 (4.3) 16 (5.2) 2 (1.8) < 0.001
 Possibly 88 (21.1) 79 (25.6) 9 (8.2)
 Probably 130 (31.1) 100 (32.5) 30 (27.3)
 Certainly 182 (43.5) 113 (36.7) 69 (62.7)
Do you follow a resuscitation strategy aiming at normalizing capillary refill time, n (%)
 Never 218 (52.2) 184 (59.7) 34 (30.9) < 0.001
 Sometimes 175 (41.9) 116 (37.7) 59 (53.6)
 Always 25 (6.0) 8 (2.6) 17 (15.5)
Is there a capillary refill time goal directed therapy-based protocol in your institution, n (%)
 No 375 (89.7) 282 (91.6) 93 (84.5) 0.093
 Yes 13 (3.1) 7 (2.3) 6 (5.5)
 I don’t know 30 (7.2) 19 (6.2) 11 (10.0)
Do you report capillary refill time in the medical record (%)
 Never 113 (27.0) 109 (35.4) 4 (3.6) < 0.001
 Sometimes 226 (54.1) 174 (56.5) 52 (47.3)
 Always 79 (18.9) 25 (8.1) 54 (49.1)
Do you personally perform capillary refill time?
 Yes 342 (81.8) 233 (75.6) 109 (99.1) < 0.001