Table 1.
Viral titer information and virus lineage assignment through whole genome sequencing [[66], [67], [68]] of SARS-CoV-2 NP/OP samples treated with FRIL and CTB-ACE2 antiviral trap proteins and assessed by microbubble SARS-CoV-2 antigen assay and RAPID. In order to access SARS-CoV-2 genome sequence, please use link as an example- https://www.ncbi.nlm.nih.gov/nuccore/ON495672.1/
| Sample | Actual sample type | Virus titer per uL RNA (N1 qPCR) | Virus titer per uL neat sample * | Variant of Concern | Assignment method | VSP ID | NCBI Accession numbers |
|---|---|---|---|---|---|---|---|
| 620 | NP/OP | 8.33E+02 | 2.98E+02 | Omicron | WGS | VSP3590 | ON495672 |
| 613 | NP/OP | 2.78E+04 | 9.93E+03 | Omicron | WGS | VSP3583 | ON480514 |
| 614 | NP/OP | 1.40E+01 | 5.00E+00 | Omicron | SGTF | ||
| 615 | NP/OP | 1.17E+01 | 4.18E+00 | Omicron | SGTF | ||
| 593 | NP/OP | 8.70E+02 | 3.11E+02 | No | WGS | VSP3562 | OM570126 |
| 595 | NP/OP | 9.63E+02 | 3.44E+02 | Delta | WGS | VSP3563 | OM570127 |
| 596 | NP/OP | 8.84E+03 | 3.16E+03 | Delta | WGS | VSP3564 | OM570128 |
| 597 | NP/OP | 5.30E+04 | 1.89E+04 | Delta | WGS | VSP3565 | OM570129 |
| 600 | NP/OP | 2.59E+05 | 9.25E+04 | Delta | WGS | VSP3566 | OM570130 |
| 601 | NP/OP | 1.19E+04 | 4.25E+03 | Delta | WGS | VSP3567 | OM570131 |
| 603 | NP/OP | NA | NA | Delta | Date | ||
| 605 | NP/OP | NA | NA | Delta | Date | ||
| 607 | NP/OP | NA | NA | Delta | Date | ||
| 609 | NP/OP | 5.17E+03 | 1.85E+03 | Delta | WGS | VSP3572 | OM570132 |
| 613 | NP/OP | 2.78E+04 | 9.93E+03 | Omicron | WGS | VSP3583 | ON480514 |
| 615 | NP/OP | 1.17E+01 | 4.18E+00 | Omicron | SGTF | ||
| 619 | NP/OP | 1.02E+01 | 3.64E+00 | Omicron | SGTF | ||
| 620 | NP/OP | 8.33E+02 | 2.98E+02 | Omicron | WGS | VSP3590 | ON495672 |
| 624 | ETA | 6.22E+01 | 2.22E+01 | Omicron | SGTF | ||
| 626 | ETA | 1.55E+03 | 5.54E+02 | Omicron | WGS | VSP3600 | ON495673 |
| 628 | NP/OP | NA | NA | Omicron | Date | ||
| 629 | NP/OP | NA | NA | Omicron | Date | ||
| 630 | NP/OP | NA | NA | Omicron | Date | ||
| 631 | NP/OP | NA | NA | Omicron | Date | ||
| 476 | NP/OP | 5.92E+05 | 2.11E+05 | Unknown | |||
| 482 | NP/OP | 6.32E+06 | 2.26E+06 | Unknown | |||
| 505 | NP/OP | 1.17E+06 | 4.18E+05 | Unknown |
WGS - whole genome sequencing (Polar Protocol and ARTIC primers) SGTF - S gene target failure by PCR, presumed Omicron Date - circulation at time of complete or near-complete variant dominance * adjusting for the fact that RNA from 140 μl of neat sample was eluted in 50 μL buffer NA: not available.