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. 2021 Sep 7;150(1):73–79. doi: 10.1002/ijc.33782

TABLE 1.

Demographics of women by self‐reported ethnicity with breast cancer risk factors and breast cancers in prospective PROCAS who provided a DNA sample

Asian Black Mixed Jewish BAME combined Unknown White other White British Presumed White European
Total number 123 117 48 131 419 274 159 8623 9056
Number without breast cancer 119 112 44 120 395 255 141 8039 8435
Number with breast cancer 4 5 4 11 24 19 18 584 621
%BC 3.31% 4.35% 8.33% 8.40% 5.78% 6.93% 11.32% 6.77% 6.86%
Prospective breast cancer 2 1 1 8 12 10 10 256 276
% prospective BC 1.68% 0.90% 2.22% 6.25% 2.98% 3.77% 6.62% 3.08% 3.16%
Mean 10‐year TCDR a 3.11% 3.17% 3.25% 4.46% 3.61% 3.13% 4.07% 3.56% 3.69%
IQR 1.79‐3.45 1.82‐4.11 1.83‐3.90 2.55‐5.44 1.89‐4.21 2.00‐3.79 2.28‐4.89 2.15‐4.41 2.12‐4.39
Expected cancers a 3.23 3.04 1.28 4.85 12.40 7.18 5.18 265.99 278.34
Demographic features in those without breast cancer at sampling
Median age at entry 57.1 57.1 56.8 61.0 58.4 62.8 57.8 59.7 59.8
IQR 51.86‐62.07 51.56‐60.92 51.49‐62.06 55.24‐65.78 52.29‐64.08 57.89‐68.30 51.83‐63.05 53.91‐65.17 53.92‐65.27
BMI 26.04 28.60 28.71 25.83 26.77 27.05 26.64 27.13 27.12
IQR 22.69‐28.12 24.39‐31.26 24.45‐30.67 22.29‐28.59 23.02‐28.91 23.57‐29.70 21.96‐30.03 23.36‐29.82 23.32‐29.82
Missing (n) 7 (6.0%) 21 (19.1%) 2 (4.5%) 2 (1.8%) 32 (8.2%) 21 (8.2%) 16 (11.3%) 379 (4.7%) 415 (4.9%)
Median age FFTP 26.0 24.2 23.7 26.6 25.4 23.7 27.0 25.3 25.3
IQR 23‐28.8 20‐27 19‐26 23‐29 21‐28 21‐26 23‐30 21‐29 21‐29
Nulliparous (n) 15 13 13 19 60 26 30 1186 1242
% nulliparous 12.82% 11.82% 29.55% 15.83% 15.35% 10.20% 21.28% 14.75% 14.72%
Mean age at menarche 13.1 13.3 13.3 12.7 13.1 13.0 12.6 12.8 12.8
IQR 12‐14 12‐14 12‐14 12‐14 12‐14 12‐14 12‐13 12‐14 12‐14
Postmenopausal (n) 81 64 27 92 264 207 88 5963 6258
% postmenopausal 69.23% 58.18% 61.36% 76.67% 67.52% 81.18% 62.41% 74.18% 74.19%
Mean age at menopause 48.1 47.8 47.8 49.0 48.3 47.7 49.8 48.4 48.4
IQR 46‐50 45‐51 46‐50 46‐53 46‐51 45‐51 48‐52 46‐52 46‐52
FDR breast cancer (n) 17 10 4 17 48 28 18 1145 1191
% FDR 14.29% 9.01% 8.89% 13.28% 11.91% 10.57% 11.92% 13.80% 13.67%

Abbreviations: BC, breast cancer; BMI, body mass index; FDR, first degree relative; FFTP, first full‐term pregnancy; IQR, interquartile range; TCDR, Tyrer Cuzick density residual.

a

Only includes prospective cancers not women sampled after breast cancer.