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. 2021 Sep 7;150(1):73–79. doi: 10.1002/ijc.33782

TABLE 3.

Assessment of SNP rs3803662 (TOX3) and rs2981579 (FGFR2) in different ethnicities in women without breast cancer

White Black Jewish Mixed Asian
rs3803662 no cancer
Total tested 7929 105 116 44 114
Mean OR 0.999 1.111 1.048 1.063 1.031
Heterozygous CT 2947 50 49 25 52
Homozygous TT 538 27 17 5 11
Allele Freq T 25.4% 49.5% 35.8% 39.8% 32.5%
%Homozygous TT 6.8% 25.7% 14.6% 11.4% 9.6%
T 4023 104 83 35 74
C 11 835 106 149 53 154
Significance Ref. P < .0001 P = .0012 P = .005 P = .037
rs2981579* no cancer
Total tested 8404 110 120 44 113
Mean OR 0.996 1.090 1.016 1.047 1.003
Heterozygous CT 4055 53 61 23 60
Homozygous TT 1367 39 23 11 18
Allele Freq T 40.39% 59.55% 44.58% 51.14% 42.48%
%Homozygous TT 16.27% 35.45% 19.17% 25.0% 15.93%
T 6789 131 107 45 96
C 10 019 89 133 43 130
Significance Ref. P < .0001 P = .21 P = .05 P = .57