TABLE 2.

Incidence rate ratios and 95% CIs of the self‐controlled case series analysis

		Incidence rate ratios for each postsurgery exposed time versus 5‐year prior surgery unexposed time 95% CIs
Fracture location	Average follow‐up postsurgery median (IQR)	0–5 years unadjusted	0–5 years adjusted a	0–3 years adjusted a	3.01–5 years adjusted a	0–2 years adjusted a	2.01–5 years adjusted a
Any	4.6 (2.4, 5.0)	1.57 (1.25, 1.98)	1.17 (0.86, 1.60)	1.20 (0.83, 1.72)	1.33 (0.79, 2.22)	1.11 (0.75, 1.62)	1.73 (1.08, 2.77)
Major	4.9 (2.4, 5.0)	3.12 (1.87, 5.21)	2.70 (1.31, 5.57)	2.77 (1.34, 5.75)	3.78 (1.42, 10.1)	2.49 (1.17, 5.30)	4.98 (1.94, 12.8)
Peripheral	4.6 (2.3, 5.0)	1.49 (1.08, 2.04)	0.92 (0.60, 1.42)	0.85 (0.50, 1.46)	1.06 (0.53, 2.20)	0.75 (0.43, 1.33)	1.18 (0.60, 2.30)

Abbreviations: CI, confidence interval; IQR, interquartile range.

^a Adjusted for age (in 5‐year bands) and bisphosphonate use.