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. 2021 Jul 28;42(3):338–347. doi: 10.1002/pd.6019

TABLE 2.

Stomach position at US1, US2, and US3 correlated to prenatal characteristics

Stomach position p Value
Grade 1 Grade 2 Grade 3 Grade 4
US1 n = 8 n = 13 n = 29 n = 4
Liver position at US1: Up 1 (13) 0 (0) 19 (66) 3 (75) <0.001
O/E LHR at US1 58 (49–75) 44 (39–48) 43 (40–49) 32 (29–47) 0.001
CDH severity at US1 <0.001
Mild 8 (100) 10 (77) 14 (48) 1 (25)
Moderate 0 (0) 1 (8) 14 (48) 3 (75)
Severe 0 (0) 0 (0) 1 (3) 0 (0)
N.A. 0 (0) 2 (15) 0 (0) 0 (0)
US2 n = 10 n = 10 n = 24 n = 4
Liver position at US2: Up 1 (10) 0 (0) 18 (75) 3 (75) <0.001
O/E LHR at US2 51 (47–63) 41 (32–54) 40 (34–47) 33 (30–40) 0.014
CDH severity at US2 0.001
Mild 7 (70) 5 (50) 8 (33) 0 (0)
Moderate 1 (10) 3 (30) 15 (63) 4 (100)
Severe 0 (0) 0 (0) 1 (4) 0 (0)
N.A. 2 (20) 2 (20) 0 (0) 0 (0)
US3 n = 19 n = 26 n = 45 n = 8
Liver position at US3: Up 1 (5) 0 (0) 26 (58) 7 (88) <0.001
O/E LHR at US3 58 (49–68) 46 (39–57) 43 (40–50) 29 (25–37) <0.001
CDH severity at US3 <0.001
Mild 17 (90) 19 (73) 25 (56) 1 (13)
Moderate 1 (5) 3 (12) 19 (42) 5 (63)
Severe 0 (0) 0 (0) 0 (0) 2 (25)
N.A. 1 (5) 4 (15) 1 (2) 0 (0)

Note: Data are presented as numbers (% of group total), p values represent the association (by use of the Fisher exact test for liver position or Jonckheere–Terpstra test for O/E LHR) or Spearman's rank correlation coefficient (CDH severity) between the four stomach position grades and prenatal characteristics. Bold type p values indicate statistical significance. Liver position “up”: liver intrathoracic. CDH severity: combination of O/E LHR and liver position according to Jani et al. 16 : mild (O/E LHR > 46% or O/E LHR 36%–45% + liver down), moderate (O/E LHR 36%–45% + liver up or O/E LHR 26%–35%), severe (O/E LHR ≤ 25%).

Abbreviation: CDH, congenital diaphragmatic hernia.