. 2021 Jul 20;64(10):845–852. doi: 10.1002/ajim.23276

Table 4.

Multivariable linear regression models examining associations between early serum biomarker concentrations and subsequent FEV1 decline (ml/year) in those with ≤64 ml/year FEV1‐decline^a

	Unstandardized coefficients^b		Standardized coefficients^b
	β	SE	β	p value
Doubling IL‐4^c	0.04	0.28	0.006	0.877
Doubling IL‐5^c	−1.34	0.50	−0.10	0.008
Doubling IL‐13^c	0.17	0.43	0.014	0.690
Doubling IFN‐γ^c	−0.53	0.66	−0.03	0.422
Doubling TNF‐α^c	−0.09	1.03	−0.003	0.932

Abbreviation: WTC, World Trade Center.

^{^a}

N = 699.

^{^b}

Controlling for age, smoking status, race, WTC exposure level, height, and FEV₁% predicted at time of biomarker measurement in weighted least squares regression using 1/SE of individual FEV₁ decline rates.

^{^c}

The number of biomarker concentration doubling from the 10th to 90th percentile: 3.5 for IL‐4, 2.8 for IL‐5, 3.2 for IL‐13, 1.8 for IFN‐γ, and 2.0 for TNF‐α.