TABLE 1.
Demographics in 194 Human LTs With SRA <15% versus SRA ≥15%
| SRA <15% | SRA ≥15% | P Value | |
|---|---|---|---|
| n = 140 | n = 54 | ||
| Recipient factors | |||
| Age (years) | 58 (18‐78) | 60 (24‐74) | 0.086 |
| Sex (female/male) | 47/93 | 20/34 | 0.649 |
| BMI (kg/m2) | 26.9 (16.1‐47.5) | 26.6 (17.5‐41.1) | 0.818 |
| Comorbidity | |||
| DM | 49 (35.0) | 16 (29.6) | 0.478 |
| HTN | 60 (42.9) | 24 (44.4) | 0.841 |
| CAD | 25 (17.9) | 10 (18.5) | 0.914 |
| Underlying liver disease | 0.591 | ||
| HBV | 7 (5.0) | 2 (3.7) | |
| HCV | 55 (39.3) | 22 (40.7) | |
| EtOH | 24 (17.1) | 10 (18.5) | |
| NASH | 16 (11.4) | 8 (14.8) | |
| ALF | 9 (6.4) | 3 (5.6) | |
| PBC | 2 (1.4) | 3 (5.6) | |
| Others | 27 (19.3) | 6 (11.1) | |
| Preoperative hospital stay (days) | 5 (0‐168) | 3 (0‐56) | 0.978 |
| Preoperative ICU admission | 75 (53.6) | 26 (48.1) | 0.498 |
| Laboratory data at LT | |||
| AST (IU/L) | 67 (18‐6,705) | 57 (22‐1,918) | 0.180 |
| ALT (IU/L) | 35 (9‐6,850) | 37 (8‐3,705) | 0.993 |
| Laboratory MELD | 30.9 (6.4‐46.2) | 31.4 (6.4‐45.9) | 0.922 |
| Donor factors | |||
| Age (years) | 35 (13‐74) | 43 (16‐72) | 0.074 |
| Sex (female/male) | 62/78 | 18/36 | 0.165 |
| BMI (kg/m2) | 26.3 (17.3‐53.0) | 25.8 (19.6‐38.7) | 0.907 |
| Comorbidity | |||
| DM | 8 (5.7) | 8 (14 .8) | 0.039 |
| HTN | 36 (25.7) | 14 (25.9) | 0.976 |
| CAD | 8 (5.8) | 2 (3.7) | 0.729 |
| Cause of death | 0.814 | ||
| Trauma | 49 (35.0) | 22 (40.7) | |
| CVS | 48 (34.3) | 18 (33.3) | |
| Anoxia | 41 (29.3) | 13 (24.1) | |
| Others | 2 (1.4) | 1 (1.9) | |
| Laboratory data at procurement | |||
| AST (IU/L) | 38 (9‐483) | 49 (12‐260) | 0.113 |
| ALT (IU/L) | 32 (8‐730) | 32 (11‐74) | 0.759 |
| DCD | 7 (5.0) | 3 (5.6) | >0.999 |
| HCV Ab positive | 3 (2.1%) | 2 (3.7%) | 0.619 |
| Cold ischemia time (min) | 440 (138‐878) | 419 (234‐757) | 0.590 |
| Warm ischemia time (min) | 48 (24‐79) | 49 (23‐77) | 0.834 |
| Large droplet steatosis ≥30% | 4 (2.9) | 4 (7.4) | 0.222 |
| Fibrosis on H&E and trichrome (≥F1) | 1 (0.7) | 0 | >0.999 |
Bold represent statistical significance.
Abbreviations: ALF, acute liver failure; CAD, coronary artery disease; CVS, cerebrovascular stroke; DM, diabetes mellitus; EtOH, alcohol‐associated (ethanol) liver disease; HTN, hypertension; ICU, intensive care unit; PBC, primary biliary cholangitis.