TABLE 1.
Demographic and disease data for subjects included in this study (median, range)
| All subjects (n = 75) | Subjects by site | |||
|---|---|---|---|---|
| UCIMC (n = 38) | VASDHS (n = 37) | p | ||
| Sex (M/F) | 56/19 | 22/16 | 34/3 | 0.002 |
| Diagnosis (BD/Scz/MD) | 65/5/5 | 28/5/5 | 37/0/0 | 0.001 |
| Age (years) a | 35.2, 14.5–76.0 | 28.6, 14.5–58.0 | 52.0, 26.0–76.0 | <0.0001 |
| BMI a | 29.1, 20.1–48.0 | 27.8, 20.1–39.0 | 31.0, 22.0–48.0 | 0.02 |
| Daily lithium dose (mg) | 900, 300–2400 | 900, 300–2400 | 900, 300–1800 | 0.95 |
| Saliva lithium levels (mmol/L) | 1.36, 0.23–3.54 | 1.34, 0.29–3.03 | 1.42, 0.23–3.54 | 0.32 |
| Serum lithium levels (mmol/L) | 0.58, 0.10–1.20 | 0.56, 0.10–1.14 | 0.61, 0.13–1.20 | 0.92 |
| Saliva/Serum lithium ratio | 2.44, 1.09–5.50 | 2.38, 1.09–5.50 | 2.75, 1.12–5.23 | 0.005 |
Sex and diagnosis differences were analyzed with a Fisher's exact test, with diagnoses grouped into ‘bipolar disorder’ or ‘other’; differences in continuous measures between sites were analyzed with the Mann‐Whitney U test; BD, bipolar disorder; Scz, schizophrenia or schizoaffective disorder; MD, mood disorder (major depressive disorder or anxiety).
a
Variables compared using data from the first appointment only, all other measures above used data from multiple appointments.