TABLE 3.

Functional pathways over‐represented by all PTV genes and ProxECAT significant genes

Gene set name	# Genes in Gene Set (K)	Description	# Genes in overlap (k)	k/K	p‐value	FDR
PTV genes:
REACTOME Transport of small molecules	728	Transport of small molecules	26	0.04	8.36e‐07	2.44e‐03
REACTOME Butyrophilin (BTN) family interactions	12	Butyrophilin (BTN) family interactions	4	0.33	8.96e‐06	1.29e‐02
REACTOME Ion channel transport	183	Ion channel transport	11	0.06	1.33e‐05	1.29e‐02
REACTOME Innate immune system	1117	Innate immune system	30	0.03	3.43e‐05	2.35e‐02
REACTOME Stimuli‐sensing channels	106	Stimuli‐sensing channels	8	0.08	4.03e‐05	2.35e‐02
ProxECAT genes:
NABA Core matrisome	275	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans	4	0.01	9.42e‐06	2.75e‐02