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. 2021 Aug 12;100(12):2135–2143. doi: 10.1111/aogs.14229

TABLE 2.

Diagnostic tools for evaluating the presence of retained products of conception with their four most frequently used parameters

Diagnostic tool Parameter RCTs (N = 79) Observational studies (N = 169)
Ultrasound 66/79 (83.5%) 124 (73.4%)
Endometrial thickness 24 (36.4%) 31 (25.0%)
Presence of gestational sac 15 (22.7%) 22 (17.7%)
Intrauterine remains 13 (19.7%) 15 (12.1%)
Uterus not empty 2 (3.0%) 15 (12.1%)
Clinical interpretation 32 (40.5%) 78 (46.2%)
Not specified 14 (43.8%) 32 (41.0%)
Bleeding 10 (31.3%) 32 (41.0%)
Uterine size 3 (9.4%) 12 (15.4%)
Expulsion of POC 5 (15.6%) 4 (5.1%)
Human chorionic gonadotropin 22 (27.8%) 59 (34.9%)
Not negative 5 (22.7%) 22 (37.3%)
Not specified 5 (22.7%) 12 (20.3%)
Not <10 IU/L 3 (13.6%) 2 (3.4%)
Decrease less than 50% 3 (13.6%) 4 (6.8%)
No decrease 2 (9.1%) 7 (11.9%)
Visual inspection of tissue lost 3 (3.8%) 9 (5.3%)
Not specified 2 (66.7%) 3 (33.3%)
No (complete) expulsion of POC 1 (33.3%) n.a.
Examination of POC by staff n.a. 3 (33.3%)
No tissue documented as POC n.a. 2 (22.2%)
Pathologic/histologic examination of tissue 0 (0%) 7 (4.1%)
POC histologically confirmed n.a. 5 (71.4%)
Tissue obtained at curettage n.a. 2 (28.6%)
Patients’ history 4 (5.1%) 5 (3.0%)
Not specified 2 (50.0%) 4 (80.0%)
No passage of POC 1 (25.0%) n.a.
Persistence of heavy bleeding 1 (25.0%) n.a.
Contractions, abdominal pain, bleeding n.a. 1 (20.0%)
Other 3 (3.8%) 15 (8.9%)
Not specified 2 (66.7%) 5 (33.3%)
Ongoing pregnancy 1 (33.3%) n.a.
No complete abortion n.a. 2 (13.3%)
Other n.a. 2 (13.3%)

Abbreviations: IU/L, international units per litre; n.a., not applicable; POC, products of conception; RCT, randomized controlled trial.

To aid clarity, the parameters presented are restricted to the four most commonly used. Hence, the total amount of articles reporting a particular diagnostic tool do not always correlate with the total number of articles applying one of the four relevant parameters.